Publications

Next-generation prebiotics: Maillard-conjugates of 2′-fucosyllactose and lactoferrin hydrolysates beneficially modulate gut microbiome composition and health promoting activity in a murine model

Stav Peled , Shay Freilich , Hila Hanani , Yechezkel Kashi , Yoav D. Livney
Food Research International Volume (2024), 177(113830)
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Extracting Water-Soluble Proteins from the Red Macroalgae Gracilaria sp. with Pulsed Electric Field in a Continuous Process

Mrinal Kashyap, Supratim Ghosh, Efraim Steinbruch, Klimentiy Levkov, Álvaro Israel, Kiran Bala, Yoav Livney, and Alexander Golberg
ACS Food Sci. Technol. (2023), 3, 4, 562–575
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Green leaves as a promising source for sustainable food protein: Seeking the productivity-functionality balance

Shachar Heppner, Yoav D. Livney
Trends in Food Science & Technology (2023), 142 (104207)
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Enzymatic cell wall degradation combined with pulsed electric fields increases yields of water-soluble-protein extraction from the green marine macroalga Ulva sp

Efraim Steinbruch , Julia Wise , Klimentiy Levkov , Alexander Chemodanov , Alvaro ´ Israel , Yoav D. Livney , Alexander Golberg
Innovative Food Science & Emerging Technologies (2023) 84 (103231)
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Novel Selectively Targeted Multifunctional Nanostructured Lipid Carriers for Prostate Cancer Treatment

Lital Cohen , Yehuda G. Assaraf and Yoav D. Livney
Pharmaceutics 2022, 14, 88
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Selective Targeting and Eradication of Various Human Non-Small Cell Lung Cancer Cell Lines Using Self-Assembled Aptamer-Decorated Nanoparticles

Daniel Barak ,Shira Engelberg ,Yehuda G. Assaraf and Yoav D. Livney
Pharmaceutics 2022, 14(8), 1650
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Enhancing the bioavailability of encapsulated hydrophobic nutraceuticals: Insights from in vitro, in vivo, and clinical studies

Yarden Abuhassira-Cohen, Yoav D Livney
Current Opinion in Food Science Volume 45, June 2022, 100832
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Sugar beet pectin as a natural carrier for curcumin, a water-insoluble bioactive for food and beverage enrichment: Formation and characterization

Yedidya Zagury, Shlomit David, Ravit Edelman, Roni Hazan Brill, Yoav D. Livney
Innovative Food Science & Emerging Technologies, 20 October 2021, 102858
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Oligosaccharide-lactoferrin shell-crosslinked particles for selective targeting of proteins to probiotic bacteria in the colon

Stav Peled, Yoav D.Livney
Food Hydrocolloids , 106973 2021
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The role of dietary proteins and carbohydrates in gut microbiome composition and activity: A review

Stav Peled, Yoav D.Livney
Food Hydrocolloids Volume 120, November 2021, 106911
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Targeted nanoparticles harboring jasmine-oil-entrapped paclitaxel for elimination of lung cancer cells

Shira Engelberg, Yuexi Lin, Yehuda G. Assaraf, and Yoav D. Livney
International Journal of Molecular Sciences 22(3) (2021)
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Physicochemical, rheological and digestibility characterization of starch extracted from the marine green macroalga Ulva ohnoi

Meital Kazir, Daniel Gurevich, Ari Groobman, Meghanath Prabhub, Álvaro Israel, Alexander Golberg and Yoav D.Livney
Food Hydrocolloids Volume 120, November 2021, 106892
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Plant-Based Seafood Analogs

Meital Kazir, and Yoav D. Livney
Molecules 2021, 26(6), 1559
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Targeted nanomedicine modalities for prostate cancer treatment

Lital Cohen, Yoav D. Livney, Yehuda G. Assaraf
Drug Resistance Updates Volume 56, May 2021, 100762
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Enhancing the oral bioavailability of natural astaxanthin using plant-based micro- and nano-encapsulation materials: Results of an In vitro evaluation and a cross-over study in humans

Yarden Abuhassira-Cohen , Ravit Edelman , Randa Abbas , Daniel Kurnik , Rand Shibel , Yoav D. Livney
Precision Nanomedicine, 3(4), 641-655 (2020).
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Delivery to the gut microbiota: A rapidly proliferating research field

Seifert Adi, Kashi Yechezkel, Yoav D. Livney
Advances in Colloid and Interface Science 274, 102038 (2019)
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Improved antioxidant activity, bioaccessibility and in-vivo bioavailability of EGCG by delivery in β-lactoglobulin particles

Yedidya Zagury, Meital Kazir, Yoav D. Livney
Journal of Functional Foods 52 (2019) 121–130.
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Starch from the sea: the green macroalga ulva sp. as a potential source for sustainable starch production

Meghanath Prabhu, Alexander Chemodanov, Ruth Gottlieb, Meital Kazir, Omri Nahor, Michael Gozin, Alvaro Israel, Yoav D. Livney, Alexander Golberg
Algal Research, 37, (2019) 215-227.
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Developing Body-Components-Based Theranostic Nanoparticles for Targeting Ovarian Cancer

Ravit Edelman, Yehuda G. Assaraf, Anton Slavkin, Tamar Dolev, Tal Shahar and Yoav D. Livney
Pharmaceutics, 11, (2019) 216-236
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Potato Protein- Based Carriers for Enhancing Bioavailability of Astaxanthin

Ravit Edelman, Shira Engelberg, Lulu Fahoum, Esther G Meyron-Holtz & Yoav D. Livney
Hydrocolloids, 96, (2019) 72-80
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Next-Generation Prebiotics: Protein-Oligosaccharide Conjugates, Polymers for advanced technologies

Adi Seifert, Shay Freilich, Yechezkel Kashi, Yoav D. Livney
Polymers for Advanced Technologies 2019;1–9
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β-Lactoglobulin-delivery system for enhancing EGCG biological efficacy in HFD obesity mice model

Yedidya Zagury; Saray Dadush; Ravit Edelman; Eddy Karnieli & Yoav D. Livney
Journal of Functional Foods 59 (2019) 362–370
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Selective eradication of human non-small cell lung cancer cells using aptamer-decorated nanoparticles harboring a cytotoxic drug cargo

Shira Engelberg, Einat Netzer, Yehuda G. Assaraf, and Yoav D. Livney
Cell death & disease, 10(10), 1-14,(2019).
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High-voltage pulsed electric fields preprocessing enhances extraction of starch, proteins and ash minerals from marine macroalgae Ulva ohnoi

Meghanath S. Prabhu*, Klimentiy Levkov, Yoav D. Livney, Alvaro Israel, Alexander Golberg*
ACS Sustainable Chemistry & Engineering 2019, 7, 17453-17463 .
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Cancer cell-selective clathrin-mediated endocytosis of aptamer-decorated nanoparticles

Shira Engelberg, Julia Modrejewski, Johanna G. Walter, Yoav D. Livney, and Yehuda G. Assaraf
Oncotarget, 9(30), 20993-21006, (2018)
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Extraction of proteins from two marine macroalgae, Ulva sp. and Gracilaria sp., for food application, and evaluating digestibility, amino acid composition and antioxidant properties of the protein concentrates

Meital Kazir, Yarden Abuhassira, Arthur Robin, Omri Nahor, Jincheng Luo, Alvaro Israel, Alexander Golberg, and Yoav D. Livney.
Food Hydrocolloids 87 (2019) 194–203
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Re-assembled Casein Micelles for Oral Delivery of Chemotherapeutic Combinations to Overcome Multidrug Resistance in Gastric Cancer

Maya Bar-Zeev*, Lotem Nativ^, Yehuda G. Assaraf & Yoav D. Livney
J Mol Clin Med. (2018), Vol 1, 52-61.
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Functional protein concentrates extracted from the green marine macroalga Ulva sp., by high voltage pulsed electric fields and mechanical press

Arthur Robin, Meital Kazir, Martin Sack, Alvaro Israel, Wolfgang Frey, Georg Mueller, Yoav D. Livney & Alexander Golberg
ACS Sustainable Chem. Eng., 2018, 6 (11), pp 13696–13705.
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β-Casein micelles for oral delivery of SN-38 and elacridar to overcome BCRP-mediated multidrug resistance in gastric cancer

Maya Bar-Zeev, Daniel Kelmansky, Yehuda G. Assaraf, Yoav D. Livney
European Journal of Pharmaceutics and Biopharmaceutics, Volume 133 (2018) 240-249
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Targeted nanomedicine for cancer therapeutics: Towards precision medicine overcoming drug resistance

Bar-Zeev, M., Livney, Y. D., & Assaraf, Y. G.
Drug Resistance Updates, 31, 15-30 (2017).
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Harnessing Proteins to Control Crystal Size and Morphology, for Improved Delivery Performance of Hydrophobic Bioactives, using Genistein as a Model

G. Israeli-Lev, M. Pitchkhadze, S. Nevo, L. Fahoum, E. Meyron-Holtz, and Y. D. Livney,
Food Hydrocolloids 63, (2017), 97–107
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A Milkfat Globule Membrane-Inspired Approach for Encapsulation of Emulsion Oil Droplets

Y. D. Livney, E. Ruimy, A. M. Ye, X. Zhu, and H. Singh
Food Hydrocolloids 65 (2017): 121-129
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The bioavailability of vitamin D, a model hydrophobic nutraceutical, in casein micelles, as model protein nanoparticles: Human clinical trial results.

Y. Cohen*, S. Ish-Shalom, E. Segal, O. Nudelman, A. Shpigelman* & Y. D. Livney
Journal of Functional Food 30 (2017) 321–325
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Hyaluronic acid – serum albumin conjugate based nanoparticles for targeted cancer therapy

R. Edelman*, Y. G. Assaraf, I. Levitzky, T. Shahar, and Y. D. Livney
Oncotarget. (2017); 8(15): 24337–24353
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Re-assembled casein micelles improve in vitro bioavailability of vitamin D in a Caco-2 cell model

Yifat Cohen*, Moran Levi^, Uri Lesmes, Marielle Margier, Emmanuelle Reboul, and Yoav D. Livney
https://pubs.rsc.org/en/content/articlehtml/2011/fo/c7fo00323d
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Albumin and Hyaluronic Acid-Coated Superparamagnetic Iron Oxide Nanoparticles Loaded with Paclitaxel for Biomedical Applications

Elena Vismara, Chiara Bongio, Alessia Coletti, Ravit Edelman*, Andrea Serafini, Michele Mauri, Roberto Simonutti, Sabrina Bertini, Elena Urso, Yehuda G. Assaraf and Yoav D. Livney
Molecules (2017), 22, 1030
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Potato Protein Based Nanovehicles for Health Promoting Hydrophobic Bioactives in Clear Beverages

S. David, and Y. D. Livney
Food Hydrocolloids 57 (2016) 229-235
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Bioavailability, Rheology and Sensory Evaluation of Fat-free Yogurt Enriched with VD3 Encapsulated in Re-assembled Casein Micelles

Y. Levinson, S. Ish-Shalom, E. Segal, and Y. D. Livney
Food & Function 7 (2016), 1477-1482
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β-Casein Nano-vehicles for Oral Delivery of Chemotherapeutic Combinations Overcoming P-glycoprotein-Mediated Multidrug Resistance in Human Gastric Cancer

M. Bar Zeev, Y. G. Assaraf, and Y. D. Livney
Oncotarget, 7 (2016), No. 17, 23322- 23334
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Soy β-Conglycinin-Curcumin Nanocomplexes for Enrichment of Clear Beverages

S. David, Y. Zagury , and Y. D. Livney
Food Biophysics 10(2) (2015), 195-206
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The Effect of Sugar Stereochemistry on Protein Self-Assembly: The Case of β-Casein Micellization in Different Aldohexose Solutions

O. Setter, and Y. D. Livney
Physical Chemistry-Chemical Physics (2015) 17, 3599.
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Sugar Stereochemistry Effects on Water Structure and on Protein Stability: The Templating Concept

R. Edelman, I. Kusner, R. Kisiliak, S. Srebnik and Y. D. Livney
Food Hydrocolloids 48 (2015) 27-37.
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Self-assembly of Hydrophobin and its Co-assembly with Hydrophobic Nutraceuticals in Aqueous Solutions: Towards Application as Delivery Systems

G. Israeli-Lev, and Y. D. Livney
Food Hydrocolloids 35 (2014) 28-35
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β-Lactoglobulin-Naringenin Complexes: Nano-Vehicles for the Delivery of a Hydrophobic Nutraceutical

A. Shpigelman, Y. Shoham, G. Israeli-Lev, and Y. D. Livney
Food Hydrocolloids 40 (2014) 214-224
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Soybean β-Conglycinin Nanoparticles for Delivery of Hydrophobic Nutraceuticals

Y. Levinson, G. Israeli-Lev, and Y. D. Livney
Food Biophysics 9(4) (2014), 332-340
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Mechanisms of Saccharide Protection Against Epigallocatechin-3-Gallate Deterioration in Aqueous Solutions

A. Shpigelman, A. Zisapel, Y. Cohen, and Y. D. Livney
Food Chemistry 139 (2013) 1105–1112.
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Hydration-Mediated Effects of Saccharide Stereochemistryon Poly(N-isopropylacrylamide) Gel Swelling

N. Manukovsky, A. Shpigelman, R. Edelman, and Y. D. Livney
Journal of Polymer Science: Part B: Polymer Physics 47 (2011) 523-530.
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β-Casein Nanoparticle-Based Oral Drug Delivery System for Potential Treatment of Gastric Carcinoma: Stability, Target-Activated Release and Cytotoxicity

A. Shapira, I. Davidson, N. Avni, Y. G. Assaraf, and Y. D. Livney
European Journal of Pharmaceutics and Biopharmaceutics 80 (2) (2012), 298–305.
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Maillard-Reaction Based Nano-Capsules for Protection of Water-Insoluble Nutraceuticals in Clear Drinks

G. Markman, and Y. D. Livney
Food & Function (2012) 3, 262-270.
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Thermally-Induced β-Lactoglobuline-EGCG Nanovehicles: Loading, Stability, Sensory and Digestive-Release Study

A. Shpigelman, Y. Cohen, and Y. D. Livney
Food Hydrocolloids 29 (2012) 57-67
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Stability and Bioavailability of Vitamin D Nanoencapsulated in Casein Micelles

M. Haham, S. Ish-Shalom (equally contributing first authors), M. Hefetz-Kustanovich, M. Nodelman, and Y. D. Livney
Food & Function (2012) 3, 737-744
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Isomeric Sugar Effects on Thermal Phase Transition of Aqueous PNIPA Solutions, Probed by ATR-FTIR Spectroscopy; Insights to Protein Protection by Sugars

A. Shpigelman, Y. Paz, O. Ramon, and Y. D. Livney
Colloid and Polymer Science 289 ,281-290, (2011) .
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Re-assembled Casein Micelles and Casein Nanoparticles as Nano-Vehicles for ω-3 Polyunsaturated Fatty Acids

P. Zimet, D. Rosenberg, and Y. D. Livney
Food Hydrocolloids 25 (2011) 1270-1276
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Microcalorimetric Study of the Effects of a Chaotropic Salt, KSCN, on the Lower Critical Solution Temperature (LCST) of Aqueous Poly(N-isopropylacrylamide) (PNIPA) Solutions

I. Shechter, O. Ramon, Y. Paz, and Y. D. Livney
Macromolecules 43 480–487, (2010) .
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Beta-Casein Nanovehicles for Oral Delivery of Chemotherapeutic Drugs

A. Shapira, Y. G. Assaraf, and Y. D. Livney
Nanomedicine: Nanotechnology, Biology and Medicine 6 , 119-126,(2010).
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Arabinogalactan-Folic acid-Drug Conjugate for Targeted Delivery and Target-Activated Release of Anticancer Drugs to Folate Receptor-Overexpressing Cells

R. I. Pinhassi, Y. G. Assaraf, S. Farber, M. Stark, D. Ickowicz, S. Drori, A. J. Domb, and Y. D. Livney
Biomacromolecules, 11, 294-303,(2010).
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Thermally-Induced Protein- Polyphenol Co-Assemblies: Beta lactoglobulin-Based complexes as Protective Nanovehicles for EGCG

A. Shpigelman, G. Israeli, and Y. D. Livney
Food Hydrocolloids 24 , 735-743,(2010).
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Beta-Casein Based Nano-Vehicles for Oral Delivery of Chemotherapeutic Drugs: Drug-Protein Interactions and Mitoxantrone Loading Capacity

A. Shapira, G. Markman, Y. G. Assaraf, and Y. D. Livney
Nanomedicine: Nanotechnology, Biology and Medicine 6 , 547-555,(2010).
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Beta-Lactoglobulin – Polysaccharide Complexes as Nanovehicles for Hydrophobic Nutraceuticals in Non-Fat Foods and Clear Beverages

N. Ron, P. Zimet, J. Bargarum, and Y. D. Livney
International Dairy Journal 20, 686-693, (2010).
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Beta-casein Nanoparticles as an Oral Delivery System for Chemotherapeutic Drugs: Impact of Drug Structure and Properties on Co-assembly

A. Shapira, D. Epstein, Y. G. Assaraf, and Y. D. Livney
Pharmaceutical Research 27, 2175–2186 , (2010) .
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Beta-Lactoglobulin and its Nanocomplexes with Pectin as Vehicles for ω-3 Polyunsaturated Fatty Acids

P. Zimet, and Y. D. Livney
Food Hydrocolloids 23 , 1120–1126, (2009).
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Casein Micelle as a Natural Nano-Capsular Vehicle for Nutraceuticals

E. Semo, E. Kesselman, D. Danino, and Y. D. Livney
Food Hydrocolloids 21 , 936-942,(2007).
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Saccharide-Structure Effects on Poly N-Isopropylacrylamide Phase Transition in Aqueous Media: Reflections on Protein Stability

A. Shpigelman, I. Portnaya, O. Ramon, and Y. D. Livney
Journal of Polymer Science: Part B: Polymer Physics 46 ,2307-2318,(2007) .
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Micellization of Bovine β-Casein Studied by Isothermal Titration Microcalorimetry and Cryogenic-Transmission Electron Microscopy

I. Portnaya, U. Cogan, Y. D. Livney, O. Ramon, K. Shimoni, M. Rosenberg, and D. Danino
Journal of Agricultural and Food Chemistry 54 , 5555-5561, (2006) .
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